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Check out the latest articles on von Willebrand disease

Last update : Thursday May 23, 2024

Variant mapping using mass spectrometry-based proteotyping as a diagnostic tool in Von Willebrand Disease

Von Willebrand disease (VWD) is the most common inherited bleeding disorder, characterized by either partial or complete von Willebrand factor (VWF) deficiency or by the occurrence of VWF proteoforms of...
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Journal of Thrombosis and Haemostasis 2024; AOP:10.1016/j.jtha.2024.04.011
Kreft, Iris C. et al.

Type 2M/2A von Willebrand disease: A shared phenotype between type 2M and 2A.

Four variants have been continuously subjected to debate and received different von Willebrand disease (VWD) classifications: p.R1315L, p.R1315C, p.R1374H, and p.R1374C. We chose to comprehensively investigate...
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Blood advances 2024 Feb
Seidizadeh Omid et al.

Awareness of von Willebrand disease among gynecologists: Investigating the referral of women with heavy menstrual bleeding to hematologists

Von Willebrand disease (VWD) is the most prevalent inherited bleeding disorder (BD), affecting up to 1% of the general population. Over 75% of women with VWD experience heavy menstrual bleeding (HMB),...
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International Journal of Gynecology & Obstetrics 2024; AOP: 10.1002/ijgo.15546
Jolana Schmiedl et al.

Type 1 VWD classification revisited: novel insights from combined analysis of the LoVIC and WiN studies

There is significant ongoing debate regarding type 1 von Willebrand disease (VWD) defintion. Previous guidelines recommended patients with von Willebrand factor (VWF) levels <30 IU/dL be diagnosed type 1 VWD, whereas patients with significant bleeding and VWF levels from 30 to 50 IU/dL be diagnosed with low VWF. To elucidate the relationship between type 1 VWD and low VWF in the context of age-induced increases in VWF levels, we combined data sets...
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Blood 2024; 143(14): 1414-24
Atiq, Ferdows et al.

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