Von Willebrand disease (VWD) is a highly heterogeneous inherited bleeding disorder caused by reduced levels or activity of von Willebrand factor (VWF). VWD is associated with a wide spectrum of clinical...
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Since the first description of a patient with von Willebrand disease (VWD) back in 1926, significant advances have been made in understanding the biology of von Willebrand factor (VWF). Under normal conditions,...
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Hemorrhagic events in von Willebrand disease (VWD) impair patients’ physical health, daily functioning, and psychological/emotional well-being. While few studies have assessed health-related quality...
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von Willebrand disease (VWD) is known as the most common inherited bleeding disorder. Despite this, some uncertainty remains regarding its prevalence and the distribution of different phenotypes worldwide and across ethnic groups. By leveraging genetic epidemiology approaches that enable population-scale estimates, the prevalence of VWD and its diverse phenotypes can be assessed more precisely. We estimated the global VWD prevalence and its distribution...
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