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Consultez les derniers articles autour de la maladie de Willebrand

Dernière mise à jour : Jeudi 03 octobre 2024

The necessity of repeat testing for von Willebrand disease in adult patients with mild to moderate bleeding disorders

In patients with a mild-to-moderate bleeding disorders (MBD), von Willebrand disease (VWD) is diagnosed at von Willebrand factor (VWF) levels ≤50 IU/dL. Although VWF levels are unstable, repeated testing...
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Journal of Thrombosis and Haemostasis 2023; aop:10.1016/j.jtha.2023.09.010
Mehic, Dino et al.

Does the VWF:CB Assay Help to Diagnose von Willebrand Factor Deficiency in Patients With a Bleeding Disorder of Unknown Cause?

von Willebrand disease (VWD) is an inherited bleeding disorder, caused by a von Willebrand Factor (VWF) deficiency. It can be due to decreased production with low plasma levels, structural anomalies, or...
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International Journal of Laboratory Hematology 2024; AOP: 10.1111/ijlh.14371
Marc Trossaërt et al.

Type 2N von Willebrand disease: genotype drives different bleeding phenotypes and treatment needs

Type 2 Normandy von Willebrand disease (VWD2N) is usually perceived as a mild bleeding disorder that can be treated with desmopressin (DDAVP). However, VWD2N patients can be compound heterozygous or homozygous...
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Journal of Thrombosis and Haemostasis 2024; 22(10): 2702-12
Daniel, Mélanie Y. et al.

Prevalence and characterization of anti-VWF antibodies in a population of subjects with type 3 VWD.

Von Willebrand disease (VWD) is an inherited bleeding disorder caused by quantitative or qualitative defects in the von Willebrand factor protein (VWF). Type 3 VWD has a severe bleeding phenotype caused by the absence of VWF where treatment usually involves replacement therapy with VWF-containing products. The immune system can react to the VWF product and form anti-VWF antibodies to neutralize or clear the VWF which can compromise efficacy of treatment...
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Blood advances 2024 Aug
Perry Crystal L et al.

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