Consultez les derniers articles autour de la maladie de Willebrand
Dernière mise à jour : Jeudi 03 octobre 2024In patients with a mild-to-moderate bleeding disorders (MBD), von Willebrand disease (VWD) is diagnosed at von Willebrand factor (VWF) levels ≤50 IU/dL. Although VWF levels are unstable, repeated testing...
Lire la suite
von Willebrand disease (VWD) is an inherited bleeding disorder, caused by a von Willebrand Factor (VWF) deficiency. It can be due to decreased production with low plasma levels, structural anomalies, or...
Lire la suite
Type 2 Normandy von Willebrand disease (VWD2N) is usually perceived as a mild bleeding disorder that can be treated with desmopressin (DDAVP). However, VWD2N patients can be compound heterozygous or homozygous...
Lire la suite
Von Willebrand disease (VWD) is an inherited bleeding disorder caused by quantitative or qualitative defects in the von Willebrand factor protein (VWF). Type 3 VWD has a severe bleeding phenotype caused by the absence of VWF where treatment usually involves replacement therapy with VWF-containing products. The immune system can react to the VWF product and form anti-VWF antibodies to neutralize or clear the VWF which can compromise efficacy of treatment...
Lire la suite
2 Application of genetic testing for the diagnosis of von Willebrand disease
Journal of Thrombosis and Haemostasis 2024; 22(8): 2115-28