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Publications on  Friday March 07, 2025
2025 Clinical Trials Update on Hemophilia, VWD, and Rare Inherited Bleeding Disorders
Am J Hematol. 2025
Clinical trial programs for inherited bleeding disorders feature an array of innovative prophylaxis options: engineered clotting factor concentrates, FVIIIa mimetics, gene therapies, and biologics to bolster...
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Role of von Willebrand factor, platelets, and aberrant flow in the initiation of venous thrombosis.
Science advances 2025 Feb; 11(6): eadr5250
Deep vein thrombosis is a major cause of morbidity and mortality worldwide. However, because of the absence of overt blood vessel damage, how venous thrombosis is actually initiated remains unclear. Using...
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Current Diagnosis of von Willebrand Disease in Italy: 3 Years Following the Release of the International Guidelines.
Seminars in thrombosis and hemostasis 2024 Jul
The American Society of Hematology-International Society on Thrombosis and Haemostasis-National Hemophilia Foundation-World Federation of Hemophilia 2021 International Guidelines (IGL) on von Willebrand...
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Platelet-Type von Willebrand Disease: Complex Pathophysiology and Insights on Novel Therapeutic and Diagnostic Strategies.
Seminars in thrombosis and hemostasis 2024 Aug
von Willebrand disease (VWD) is the most common well-studied genetic bleeding disorder worldwide. Much less is known about platelet-type VWD (PT-VWD), a rare platelet function defect, and a "nonidentical"...
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