The regulated secretion of von Willebrand factor (VWF) from Weibel-Palade bodies (WPBs) in endothelial cells is fundamental to hemostasis. This process relies on recruiting Rab GTPases and their effectors... HTML Version |
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The global population is ageing and this demographic shift has profound effects on haemostasis, notably a progressive tilt towards a hypercoagulable state. A major age-associated change in haemostasis... HTML Version |
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Though tonsillectomies are commonly performed in children, the rate of post-tonsillectomy hemorrhage in those with von Willebrand disease (VWD) is unknown.
Objectives: To determine the rate of post-tonsillectomy... HTML Version |
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Treatment for von Willebrand disease (VWD), the most common inherited bleeding disorder, has advanced considerably since its initial description by Erik von Willebrand first described a family in the Åland... Read more
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