Idioma:   FR    EN   ES  

Noticias

Consulte los últimos artículos sobre la enfermedad de von Willebrand

Última actualización: Jueves, 06 de febrero de 2025

Pregnancy loss in individuals with von Willebrand disease and unspecified mucocutaneous bleeding disorders: a multicenter cohort study

While bleeding around pregnancy is well described in von Willebrand disease (VWD), the risk of pregnancy loss is less certain. We aimed to describe the frequency of pregnancy loss in females with VWD compared...
Leer más

Journal of Thrombosis and Haemostasis 2025; 23(2): 429-39
Skeith, Leslie et al.

Adherence and Quality of Life in Adult Patients With Haemophilia A, Haemophilia B and Von Willebrand Disease: A National Cross-Sectional Survey

New treatments for patients with bleeding disorders (PWB) have emerged, including products with extended half-life and subcutaneous administration. These less frequent treatments can potentially enhance...
Leer más

Eur J Haematol, 114: 164-172.
Clausen et al.

The future of siRNA-mediated approaches to treat von Willebrand disease

The clinical management of the inherited bleeding disorder von Willebrand disease (VWD) focuses on normalizing circulating levels of von Willebrand factor (VWF) and factor VIII (FVIII) to prevent or control...
Leer más

Expert Review of Hematology, 17:10, 713-721
Noa A. Linthorst et al.

Amelioration of a von Willebrand disease type 2B phenotype invivo upon treatment with allele-selective siRNAs.

Treatment options for the bleeding disorder von Willebrand disease type 2B (VWD2B) are insufficient and fail to address the negative effects of circulating mutant von Willebrand factor (VWF). The dominant-negative nature of VWD2B makes functionally defective VWF an interesting therapeutic target. Previous in vitro studies have demonstrated the feasibility of allele-selective silencing of mutant VWF using small interfering RNAs (siRNAs) targeting...
Leer más

Blood advances 2025 Jan; 9(2): 310-320
Linthorst Noa A et al.

TOP 3 artículos más leídos

Búsqueda bibliográfica

Refine su búsqueda de información científica

Búsqueda Avanzada ¿Necesita ayuda?

Búsqueda por revista:
179 artículos actualmente disponibles


Descubra WillebrandXPERTy todas las funcionalidades en unos instantes