Von Willebrand disease (VWD) is the commonest inherited bleeding disorder with approximately one in 1000 of the population experiencing bleeding symptoms due to either reduced levels or dysfunctional von...
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This guideline updates the previous guidelines published on behalf of the British Society for Haematology (BSH) and the United Kingdom Haemophilia Centre Doctors' Organisation (UKHCDO), focussing on the...
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Evaluating a patient suspected of having a mild to moderate bleeding disorder (MBD) is one of the more challenging tasks in hematology. Many features of the bleeding history are subjective, distinguishing...
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Antifibrinolytic agents are frequently used to treat patients with bleeding disorders. These agents are lysine analogues that exert their haemostatic effects by binding to plasminogen and inhibiting its interaction with fibrin, thus reducing fibrinolysis. Antifibrinolytics have been shown to be effective in numerous clinical settings, including surgery, oral bleeding, epistaxis, and menorrhagia; their efficacy is maintained in patients with and without...
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