Evaluating a patient suspected of having a mild to moderate bleeding disorder (MBD) is one of the more challenging tasks in hematology. Many features of the bleeding history are subjective, distinguishing...
Lire la suite

Antifibrinolytic agents are frequently used to treat patients with bleeding disorders. These agents are lysine analogues that exert their haemostatic effects by binding to plasminogen and inhibiting its...
Lire la suite

In the last several decades, the bleeding disorders community has seen an unprecedented evolution of novel therapies for treating inherited disorders. These therapies have included recombinant clotting...
Lire la suite

Von Willebrand disease (VWD) is a hemostatic disorder characterized by a quantitative or qualitative deficiency of the Von Willebrand factor (VWF). It affects males and females equally. This pathology has more severe clinical manifestations in females of reproductive age, with a mean age of diagnosis at 19 years. In the pregnant patient, Von Willebrand disease poses an increased risk of complications during labor or the postpartum period, attributed...
Lire la suite